1. Can doctors accurately predict which people with carotid artery disease are most at risk of a stroke?

2. Is there an association between carotid disease and cognitive decline? 

3. What is the optimal management of patients with carotid disease using individualised risk benefit ratios?

4. Can the appearance of carotid narrowings (plaques) help predict an individual patient’s stroke risk?

5. What is the best treatment for carotid artery disease? E.g. medicines, lifestyle changes, intervention.

6. What can be done to prevent re-narrowing and recurrent symptoms following carotid surgery?

7. Is screening for carotid artery disease worthwhile, and if so, what is the best screening test?

8. Following carotid surgery, is surveillance (i.e, scanning to detect re-narrowing) of the treated artery necessary?

9. Is surveillance of patients with known carotid artery disease worthwhile?

10. What is the optimal antiplatelet regime following carotid endarterectomy?

The process of developing these 10 reserch priorities is outlined in an open-access peer reviewed paper published in the Journal of the Vascular Societies of Great Britain and Ireland:

Luo X, Nortley M, Long J, Gronlund T, Bulbulia R, Halliday A, Howard DPJ, on behalf of the VSGBI Carotid Special Interest Group/James Lind Alliance Priority Setting Partnership. Research Priorities for Carotid Conditions: results of the UK Vascular James Lind Alliance Priority Setting Process. J.Vasc.Soc.G.B.Irel. 2023;2(3):134-140. http://doi.org/10.54522/jvsgbi.2023.071